apcgenemutation

2024年2月25日 — FAP and AFAP are caused by mutations in the APC gene. These conditions are rare, occurring in about one in 10,000 people. People with FAP may ...

Mutations in the APC gene may result in colorectal cancer and desmoid tumors. APC. Available structures.

Several mutations in the APC gene have been found in people with a type of aggressive but noncancerous (benign) growth called a desmoid tumor. These rare tumors ...

In 1997, a Johns Hopkins research team found an inherited genetic mutation called APC I1307K. Adenomatous polyposis coli (APC) is a gene that suppresses ...

由 B Li 著作 · 2023 · 被引用 4 次 — APC (adenomatous polyposis coli) gene mutation is a central initialization in colon cancer tumorigenesis. However, the connection between APC ...

由 W Hankey 著作 · 2018 · 被引用 167 次 — Biallelic mutation of the APC gene occurs in 45%–80% of colorectal cancers [5–7] and is observed in the earliest detectable lesions [2]. The APC locus was ...

由 LN Kwong 著作 · 2009 · 被引用 333 次 — Colon cancer closely follows the paradigm of a single “gatekeeper gene.” Mutations inactivating the APC (adenomatous polyposis coli) gene are found in ~80% ...

2013年3月1日 — The APC gene provides instructions for making the APC protein, which plays a critical role in several cellular processes. The APC protein ...